March 25, 2026

Official Synopsis of La Jefa: What is the new Super Series about?
The story of La Jefa centers on Gloria Guzmán (played by Fabiola Guajardo), a woman who seems to have the perfect life: a successful career, a family that adores her, and she is about to marry Juan José Cruz (Cristián de la Fuente), a commander in the State Attorney General’s Office and the father of her child. However, on her wedding day, her world falls apart when a group of hitmen murder her fiancé, revealing a dark truth: Juan José had betrayed his partners in the Tijuana Cartel, stealing millions of dollars.

In an instant, Gloria loses everything. Her family turns their backs on her, the government confiscates her assets, and she is hunted by her late husband’s enemies, including the fearsome cartel leader, Duque Medina (José María Galeano). Alone, penniless, and with her son Daniel seriously ill with diabetes, Gloria is forced to make a radical decision. She stops running and uses her intelligence and audacity to enter the world of money laundering and drug trafficking. She is no longer the victim; now she is the strategist. It is the birth of a new legend, a woman who earns the respect and fear of her enemies: “La Jefa.”

Watch the Official Trailer for La Jefa

Immerse yourself in the action with the official trailer for La Jefa. Witness Gloria Guzmán’s transformation and get ready for a high-impact story that will hook you from the very first moment.

Cast of La Jefa: Who’s Who in the Telenovela?
La Jefa features a stellar cast that brings together big names from Telemundo productions, guaranteeing top-notch performances.

Main Cast
Actor Character Role in the Plot
Fabiola Guajardo Gloria Guzmán The protagonist. A mother who becomes a powerful criminal leader to save her son.
Iván Arana Eduardo Torres The male protagonist, a key and enigmatic figure in Gloria’s life.
José María Galeano Duque Medina The main antagonist, leader of the Tijuana Cartel who seeks revenge.
Azela Robinson Maribel Ortiz A con artist who plays an ambiguous role, between ally and enemy, in Gloria’s rise.
Cristián de la Fuente Juan José Cruz (Special appearance) Gloria’s fiancé, whose murder triggers the story.

Notable Supporting Cast
Mauricio Henao as Mateo Restrepo
Sara Corrales as Laura Rojas
Pepe Gámez as Sebastián Cruz
Jorge Luis Moreno as Ignacio Pérez “Don Nacho”
Guillermo Quintanilla as Venancio Estrada
Yany Prado as Yadira Castro
Verónica Merchant as Matilde de Guzmán
The cast also includes Andrés Almeida, Jesús Moré, Julieta Grajales, Uriel del Toro, among other talents.

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